Population Based Research

Below you will find information about the population based research projects that are currently underway at the CVC. Through the interrogation of registries and population health data, the CVC is steadfastly dedicated to our organization’s mission to evaluate outcomes, identify unmet needs, and inform future clinical research directions.

Acute Heart Failure – Emergency Management (AHF-EM)

Study cohort: patients presenting with suspected acute heart failure (AHF) at Edmonton hospital emergency departments (EDs) with diagnosis confirmation (e.g. by testing for AHF biomarkers such as b-type natriuretic peptide [BNP]). Data analyzed include laboratory data/biomarkers, medications, history, EF, echocardiograms (ECGs), magnetic resonance imaging (MRI), etc. from the Discharge Abstract Database (DAD) and the National […]

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Alberta CoAPT

Study cohort: Albertans diagnosed with Acute Cardiac Syndromes (ACS) for which three years of follow-up data is available, focusing on patients undergoing cardiac catheterization during the index hospitalization. Data analyzed: anatomical and clinical data entries in the APPROACH database (Alberta Provincial Project for Outcome Assessment in Coronary Heart Disease), medications data from the Pharmaceutical Information […]

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Alberta Heart Failure Etiology and Analysis Research Team (Alberta HEART)

Study cohort: Albertans with systolic and diastolic heart failure (HF) or a high risk of developing HF. High risk factors include hypertension, atrial fibrillation, obesity, diabetes, other cardiac conditions (e.g. acute coronary syndrome, chronic obstructive pulmonary disease [COPD]). Data analyzed: laboratory data/biomarkers, history, echocardiograms (ECGs), magnetic resonance imaging (MRI), etc. from the Discharge Abstract Database […]

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Alberta Population Health Laboratory

Study cohort: Albertans diagnosed with acute coronary syndromes (ACS), heart failure (HF), non-acute ischemic heart disease (IHD), ventricular arrhythmia (VA), or syncope. Data analyzed includes entries in the National Ambulatory Care Reporting System (NACRS), the Discharge Abstract Database (DAD), the Alberta Health Practitioner Claims Database, the Alberta Health Care Insurance Plan Registry, and the Alberta […]

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Canadian Population Health Laboratory

Study cohort: Canadians with acute coronary syndromes (ACS), heart failure (HF), non-acute ischemic heart disease (IHD), ventricular arrhythmia (VA), syncope, congenital heart disease (CHD) or infective endocarditis (IE) residing in all provinces except Quebec. Data analyzed includes entries in the Discharge abstract database (DAD) from the Canadian Institute of Health Information (CIHI). These data are […]

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Pregnancy Birth Cohort

Study cohort: pre-pregnancy, perinatal (pregnancy/delivery) and neonatal patients from Alberta. Data analyzed includes entries in the Discharge Abstract Database (DAD), the National Ambulatory Care Reporting System (NACRS), the Physician Claims Database, the Pharmaceutical Information Network (PIN), Alberta Vital Statistics Birth Database (ABVS-Births), and Statistics Canada. These data have been used to examine the following: Impact […]

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Vital Heart Response

Study cohort: ST-Elevated Myocardial Infarction (STEMI) Patients from Edmonton, including patients who activated the pre-hospital Vital Heart Response system, and who may have been administered the anti-platelet therapies aspirin/clopidogrel or aspirin/ticagrelor during EMS response. Data analyzed includes entries in the Vital Heart Response Patient Registry, the Discharge Abstract Database (DAD), and patient electrocardiographic (ECG) data […]

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