The biostatisticians at the CVC provide statistical expertise to study design and analysis, and have experience with a wide variety of data sources. They participate in innovative primary and secondary research in cardiovascular medicine in collaboration with local, national, and international researchers. CVC biostatisticians are closely involved in generating academic products, such as abstracts and presentations for major scientific meetings, and manuscripts published in peer reviewed journals. They also provide guidance to students, residents and junior clinical researchers in applied statistics.
With access to large population-based datasets and multinational clinical trials, the biostatistics group apply a variety of statistical methods for primary and secondary/observational studies, including descriptive analysis, survival analysis, time series analysis, longitudinal analysis, and risk adjustment and modeling. Research themes can be characterized as associations between clinical outcomes and: (i) patient-level factors, (ii) process-of-care or treatment factors; (iii) environmental or geospatial factors; or (iv) regional/international factors. Special interest has been dedicated to further develop methods related to risk prediction, composite endpoints, and more recently, big data analytics.
- Design of primary and secondary studies and research protocols
- Development of statistical analysis plans and database specifications
- Data management, including data transfer, merging, reconciliation, and validation of analysis databases
- Programming expertise in SAS and R
- Generation of statistical tables, figures, and listings and interpretation of findings
- Consultation and execution of advanced statistical methods
- Development and application of novel statistical methods